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docusate (DOC u sate)
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Colace
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50 mg
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100 mg
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Colace is available in a Syrup and Liquid
form.
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Surfak
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240 mg
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This drug is available in an over-the-counter form.
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What is docusate?
Docusate is basically a detergent that is not absorbed by
the body. It encourages the mixture of water and dietary fat
within the stool, making the stool softer. It does not hold
water like some bulking agents nor does it stimulate the
bowel like laxatives.
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What is it used for?
Docusate is most beneficial when hard stools occur and
especially when they are difficult or painful to pass. This
drug is not particularly helpful when infrequent stools or
constipation develop. Docusate is not a laxative.
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How do I take it?
Follow your physician's instructions carefully. Drink a
glass of water with each dose. The liquid may be given in
milk, fruit juice or infant formula to mask the taste.
Higher doses are recommended for initial therapy and then
the dosage can be adjusted to the individual's needs. The
effect is usually seen 1 to 3 days after the initial dose.
Store in a tightly closed container at room temperature.
Keep all medications away from children. Never share your
medications with anyone else.
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What do I do for a missed dose?
If you miss a dose of this medicine, take it as soon as
possible. If it is almost time for your next dose, skip the
missed dose and return to your regular schedule. Do not
double up on this medication.
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Are there interactions with food or beverages?
There are no known interactions with food or beverages.
An increase in fluid intake is recommended for better
results.
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Are there interactions with other drugs?
An interaction generally means that one drug
may increase or decrease the effect of another drug. Also,
the more medications a person takes, the more likely there
will be a drug interaction. Do not take docusate along with
mineral oil unless directed by your physician.
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Is there a problem if I have another disorder or
disease?
At times, a drug may have a different or enhanced effect
when other diseases are present. At other times, the drug
may worsen or effect another disease. Fiber should not be
used if there is a suspicion of a chronic bowel obstruction
unless discussed with the physician. It is also best to
temporarily restrict fiber after abdominal surgery and when
there is a flare-up of chronic bowel disorders such as
Crohn's disease and ulcerative colitis.
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What about allergies?
People who have known allergies or asthma may be at an
increased risk for a reaction from any new medication. The
physician should always know a patient's allergy history.
Signs of an allergic reaction are skin rash, hives and
itching. Of course, a person should not take docusate if
there has been a previous reaction to this or a similar
drug.
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What if I'm pregnant, considering pregnancy or
breast-feeding?
Most females now know that, if possible, no drug,
including alcohol, should be taken during pregnancy or
lactation. The potential danger, of course, is an injury to
the baby. However, some drugs are much safer than others in
this regard. So, the FDA has a grading system for each drug
which reflects what is known medically. It ranks drugs from
A, where medical studies show no evidence for danger to the
fetus or mother, to B, C, D and X, where the medical
evidence indicates that the risk to the fetus outweighs any
benefit to the mother. Docusate is ranked C. Constipation
can be a problem during pregnancy. Generally, it is safe to
increase fiber either with food or psyllium. Docusate is a
chemical; therefore, its use should be discussed with your
physician. Always consult your physician before taking any
drug during or when planning pregnancy.
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What are the effects on sexual function?
There are no known adverse effects of docusate on sexual
function.
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Are there other precautions?
- Always take docusate with plenty of fluids. Do not
use docusate if you have difficulty swallowing.
- Contact your physician if constipation persists for
more than a week with regular use of a bulk laxative or
if rectal bleeding occurs.
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How long is it safe to take docusate?
Docusate is not habit-forming and is safe for long-term
use.
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How about side effects?
Adverse reactions can occur with any drug, even
over-the-counter medications. Some of these are mild such as
a stomach upset, which may be avoided by taking the
medication with food. Minor reactions may go away on their
own but if they persist, contact the physician. For major
reactions, the patient should contact the physician
immediately.
For docusate, the following are the observed side
effects:
Minor:
- nausea
- mild abdominal cramps
- bloating
- diarrhea
- rumbling sounds
Major:
- severe abdominal pain
- vomiting
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A physician's comment...
Hard pellet stools usually reflect a condition called
diverticulosis or simple chronic constipation. An increase
in dietary fiber is usually the first and, often, the only
thing that needs to be done. Docusate, while not increasing
stool bulk like fiber, can soften hard stool pellets. When
that is the only problem, this drug can be helpful.
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Posted: July 1998
High Fiber
Diet | Diverticulosis
| Constipation
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