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Gastro Esophageal Reflux Disease GERD
Almost
everyone has experienced heartburn. About 25 million American adults
suffer daily from heartburn. It is that burning sensation felt behind
the breastbone and sometimes in the neck and throat. Heartburn is
caused by stomach acid refluxing or splashing up into the esophagus
-- the muscular tube that connects the throat to the stomach.
Occasional heartburn is nothing to be concerned about. However,
anyone who has heartburn on a regular basis should consult a
physician. Constant exposure to stomach acid can irritate the lining
of the esophagus and cause other medical problems. Serious heartburn
is known as gastroesophageal reflux disease or GERD.
What is GERD?
The esophagus carries food and liquid into the stomach. At the lower
end of the esophagus where it enters the stomach, there is a strong
muscular ring called the lower esophageal sphincter (LES). The LES
should remain tightly closed, except to allow food and liquid to pass
into the stomach. Reflux occurs when the LES is not working properly.
It may relax for periods of time throughout the day and night, or it
may be constantly too weak to function effectively. This allows the
stomach's acid juices to flow into the esophagus. How severe the
disease becomes depends on how weakened the LES is, and the amount
and duration of acid refluxed into the esophagus.
It is also common to find a hiatal hernia complicating GERD. With
a hiatal hernia, the upper part of the stomach actually pushes up
into the chest through a weakness in the diaphragm. The diaphragm is
the thin, flat muscle that separates the lungs from the abdomen. When
part of the upper stomach is stuck above the diaphragm, stomach acid
is retained there for a longer period and is more likely to reflux
into the esophagus.
Symptoms and Causes of GERD
Frequent heartburn is the most common symptom. However, patients may
also experience some of the following:
- sour or bitter taste
- bitter stomach fluid coming into the mouth, especially during
sleep
- hoarseness
- repeatedly feeling a need to clear the throat
- difficulty swallowing food or liquid
- wheezing or coughing at night
- worsening of symptoms after eating, or when bending over or
lying down.
Certain diet and lifestyle choices can contribute to the
condition. For example, certain foods increase acid production, and
fatty foods increase the time food remains in the stomach. Chocolate,
peppermint, coffee, alcoholic beverages, and especially nicotine in
cigarette smoke weaken or relax the LES. Obesity places added
pressure on the upper abdomen, and during pregnancy the LES weakens
for unknown reasons.
Complications
Complications occur when GERD is severe or long-standing. Constant
irritation of the esophagus by stomach acid can lead to inflammation,
ulcers, and bleeding. Anemia or low blood count may develop. Over
time, scarring and narrowing of the esophagus can also develop,
making it difficult to swallow foods and liquids. This narrowing is
called a stricture. Some patients develop a condition called
Barrett's esophagus, which is a serious change in the cells lining
the esophagus. Barrett's esophagus may be a forerunner of esophageal
cancer.
Diagnosis of GERD
The diagnosis can usually be suspected by the physician, simply by
taking the medical history. Beyond that, the physician may order an
x-ray examination of the esophagus and stomach. For this x-ray, the
patient swallows a liquid containing barium. This makes it possible
to see the reflux and a hiatal hernia on the x-ray. Endoscopy is the
most important test for patients with GERD. It is done with the
patient under sedation. The physician examines the lining of the
esophagus and stomach with a thin, lighted, flexible tube called an
endoscope. This exam is helpful in determining how severe the disease
is, how much tissue damage there is, and if there are any
complications. Certain conditions, such as narrowing or stricture in
the esophagus, can usually be corrected during this procedure. During
an endoscopy, the physician can also look for signs of Barrett's
esophagus, and perform a biopsy to see if precancerous changes have
occurred.
There are other tests that are helpful. A pressure recording of
the esophagus is called esophageal manometry. It measures the
pressure in the LES and any abnormal muscle contractions in the main
part of the esophagus. Finally, a 12 to 24 hour recording of the
acidity in the esophagus is often helpful.
What is the treatment?
Treatment is aimed at reducing reflux and damage to the lining of the
esophagus. Initial treatment is with lifestyle changes. Patients with
GERD should follow these recommendations:
- Avoid eating anything within three hours before bedtime.
- Stop smoking. Nicotine in the blood weakens the LES.
- Avoid fatty foods, milk, chocolate, spearmint, peppermint,
caffeine, citrus fruits and juices, tomato products, pepper
seasoning, and alcohol -- especially red wine.
- Decrease portions of food at mealtime, and avoid tight
clothing or bending over after eating.
- Review all medications with the physician. Certain drugs can
weaken the LES, allowing acid irritation of the esophagus.
- Elevate the head of the bed or mattress 6 to 8 inches. This
helps to keep acid in the stomach by gravity when sleeping. Extra
pillows by themselves are not very helpful.
- Lose weight if overweight. This may relieve upward pressure on
the stomach and LES.
Lifestyle changes are often all that is needed to correct mild
forms of GERD. When symptoms are bad or GERD is moderate to severe,
the physician will prescribe medications. Some that reduce stomach
acid include Tagamet, Zantac, Pepcid and Axid. Certain potent newer
drugs, such as Prilosec and Prevacid, can almost eliminate stomach
acid entirely. These two drugs are most frequently used when GERD is
severe. Other medications, such as Reglan (generic: metoclopramide) tighten the LES. These may be especially useful at night when reflux often occurs.
A number of patients with GERD may need surgery to strengthen the
LES. This procedure is called fundoplication. Previously this surgery
required a major operation, often through the chest. It is a
difficult operation for the patient, with a long recovery. It is now
usually done by laparoscopy. This is a new type of minimally invasive
surgery, performed with a tiny incision at the naval and a few needle
points in the upper abdomen. The patient usually returns home 1-2
days after surgery, with few problems. Surgery, however, should not
be considered until all other measures have been tried. Surgery is
often seriously considered for an otherwise healthy patient when the
disease is severe, or the patient does not want to face the expense
or regimen of long-term treatment with medications.
Summary
GERD is a common problem that requires medical attention when
symptoms and tissue damage become troublesome. Fortunately, there is
a great deal that can now be done about GERD. Lifestyle changes can
help, and there are many medications and even surgery to treat and
correct GERD. Working together with the physician, a good medical
program can almost always be developed to successfully treat the
patient with GERD.
Related Diets
GERD
| No Gastric
Irritants/Ulcers/Dyspepsia
Related Procedures
Upper GI
Endoscopy (EGD) | Esophageal
pH | Esophageal
Manometry | Correction
of Acid Reflux By Laparoscopy
This material does not cover all information and is
not intended as a subsitute for professional care. Please consult
with your physician on any matters regarding your health.
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Copyright
Chek Med Systems®, Inc., All Rights Reserved.
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